1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Dopamine Receptor
  4. D1 Receptor Isoform
  5. D1 Receptor Modulator

D1 Receptor Modulator

D1 Receptor Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-W743888
    AL-LAD
    Modulator
    AL-LAD (6-Allyl-6-nor-LSD) is an activator for 5-HT2A receptor with Ki of 3.4-8.1 nM. AL-LAD exhibits affinity for dopamine receptor D1 and dopamine receptor D2 with K0.5 of 189 nM and 12.3 nM. AL-LAD acts as psychoactive substance in mouse model.
  • HY-19733
    Lumateperone tosylate
    Modulator 99.53%
    Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.